Anti-Inflammatory activity of Morinda tinctoria on Carrageenan induced Rat Paw Edema
نویسندگان
چکیده
Morinda tinctoria (Rubiaceae) is commonly found in the regions of India, Burma, Sri Lanka, Cambodia and Indonesia. This plant is used in the treatment of asthma and bronchitis. Ethanolic extract of whole plant of M. tinctoria was screened for anti-inflammatory activity in carrageenan induced rat paw edema at the dose level 100, 200 and 400mg/kg was compared with the standard drug, Diclofenac sodium. The extract produced significant and dose dependent inhibition of carrageenan induced significant (p<0.05) when compared to control. Preliminary phytochemical analysis of M. tincloria indicated the presence of PO, GSH, Vitamin E, Vitamin C, Calcium and magnesium. Further studies may reveal the exact mechanism of action and phytochemical constituents responsible for anti-inflammatory activity.
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